铜绿假单胞菌的感染现状及临床分析

目的了解河南省胸科医院铜绿假单胞菌（PAE）的感染现状及其对抗生素的耐药性，指导临床科学治疗，控制感染。方法回顾性调查2009年6月—2011年6月河南省胸科医院各病房患者感染铜绿假单胞菌的情况，对其来源和耐药性及相关危险因素进行分析。结果1420例临床标本中获得铜绿假单胞菌163株，阳性率11．5％；呼吸科和心脏外科ICU是铜绿假单胞菌检出率最高的病房，其构成比分别是27．6％和21．5％；PAE耐药率较高的抗生素分别是磺胺甲基异恶唑62．6％头孢哌酮45．4％和头孢曲松42．9％。结论为有效控制铜绿假单胞菌的耐药率，应科学使用抗生素，减少经验性用药，同时严防医院感染的发生。

Clinical analysis of Pseudomonas aeruginosa and its infection status

Objective To understand the infection status and drug resistance of Pseudomonas aeruginosa, for scientific treatment and control of infection. Methods Retrospectively analyzed the infection status of Pseudomonas aeruginosa in our hospital from June. 2009 to June. 2011. Analyzed the source, drug resistance and related risk factors. Results In 1 420 clinical specimens, 163 were Pseudomonas aeruginosa,positive rate were 11.5%. The highest detection rate of department of respiration and surgical ICU were 27. 6% and 21.5%. The high resistance rate of PAE were Sinomin in 62. 6%, Cef- operazone in 45.4% and Cefatriaxone in 42. 9%. Conclusion For effective control of drug resistance rate of Pseudomonas aeruginosa,we should use of antibiotics scientifically,reduce empiric therapy and prevent hospital infection.