急性重症胰腺炎手术干预及其预后分析

目的探讨手术干预治疗急性重症胰腺炎的临床效果及其预后。方法回顾性分析2007年3月—2011年2月邯郸市中心医院收治的急性胰腺炎患者182例患者，根据治疗方式的不同分为手术组与非手术组各91例，比较两组患者在C反应蛋白（CRP）、APACHE-Ⅱ评分、住院时间以及术后病死率、再手术及术后并发症方面的差异。结果非手术组APACHE—Ⅰ／评分及CRP数值达到较高水平，手术组相比有显著性差异（P〈0．01），住院时间手术组比非手术组组明显缩短（P〈0．01）；手术组手术时的全身情况比非手术组手术时佳，非手术组在术后经常出现肠瘘、胰瘘等外科手术并发症，同时由此导致的发病几率显著提高（P〈0．01）；非手术组与手术组，在病死率与并发症发生率方面进行显著性分析，两者有统计学意义（P〈0．01）。结论急性重症胰腺炎外科手术治疗是最有效的方法。

Analysis of surgical intervention and prognosis of severe acute pancreatitis

Objective To investigate the clinical effect of surgical intervention on the prognosis of severe acute pancreatitis. Methods Retrospective analysis of each of 91 cases from March 2007 to February 2011 in our hospital 182 patients with acute pancreatitis, according to the different treatment modalities were divided into surgery and non - srugical group, the two groups were compared in CRP, APACHE - II score, length of hospital stay and postoperative mortality, reopera- tion, and postoperative complication difference. Results Of the non - surgical group APACHE - II score and CRP values reached a high level, there was significant difference （ P 〈 0. 01 ） , duration of hospitalization, surgery groupgroup was significantly shorter than that of the non - surgical （ P 〈 0. 01 ） compared with the surgery group ; Operation group the surgery general condition was good that of than non - surgical group, the non - surgical group after frequent surgical compli- cation, such as intestinal fistula, pancreatic fistula, and the resulting risk of disease significantly increased （P 〈 0. 01 ） ; Non - surgical group in terms of mortality and the incidence of complications with the surgery group were analyzed, a significant difference （ P 〈 0. 01 ） between the two groups. Conclusions For the majority of cases, acute pancreatitis surgical treatment is the most effective method.