Can nearly finished medical students interpret their professional literature?

The ability of senior medical students to interpret clinical research articles was examined by means of a written examination based upon two papers from general medical journals. The subjects of the articles were a diagnostic test and a therapeutic trial respectively. Knowledge of basic methodological and statistical concepts mentioned in the articles was in 86% of the students examined (n = 90) below the minimal level required for correct interpretation. 60% of the participants could not correctly apply the results mentioned in the diagnostic paper to a written clinical problem, and 11% could not apply the result of the therapeutic trial. From the reasons the participants gave for their decisions it appeared that 77% and 35% respectively had not been able to interpret the articles correctly. A comparison between self-rated knowledge and results of the test showed that the students tended to overestimate their knowledge. Knowledge of basic concepts of clinical epidemiology and statistics of these nearly graduated medical doctors is insufficient, and many of them cannot interpret clinical research articles correctly.