| 男性不育患者年龄对精子形态及精子DNA完整性的影响分析 |
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| 引用本文： | 刘安娜.男性不育患者年龄对精子形态及精子DNA完整性的影响分析[J].中国优生与遗传杂志,2014(5):131-131,63. |
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| 作者姓名： | 刘安娜 |
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| 作者单位： | 中国人民解放军第一七四医院检验科、厦门大学附属成功医院,福建厦门361003 |
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| 摘 要： | 目的探讨男性不育患者年龄对精子形态及精子DNA完整性的影响。方法将231例男性不育患者按年龄分为A组（25—40岁）及B组（≥40岁），对其进行精子形态学分析及精子DNA完整性检测。结果A组精子畸形率及精子DNA碎片指数（DFI）明显低于B组（P〈0．05），两组差别有显著性意义。结论男性年龄对精子形态及精子DNA完整性有一定的影响，应引起临床关注。
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| 关 键 词： | 男性不育 年龄 精子形态 精子DNA完整性 |
Analysis of effects of sterile patient ages on sperm morphology and sperm DNA integrity |
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| LIU An-na.Analysis of effects of sterile patient ages on sperm morphology and sperm DNA integrity[J].Chinese Journal of Birth Health & Heredity,2014(5):131-131,63. |
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| Authors: | LIU An-na |
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| Institution: | LIU An-na. (The Clinical Lab Department of the 174th Hospital of PLA Xiamen University Affiliated Chenggong Hospital, Xiamen, 361003 ) |
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| Abstract: | Objective.. To explore the effects of age on morphology and DNA integrity of sperms in sterile patients. Methods. 231 sterile patients were divided into group A （25-40 years old） and group B （ ≥ 40 years old） , and the morphology and DNA integrity of sperms in each group were determined. Results： Rate of teratosperm and DNA fragment index （DFI） in group A were apparently lower than in group B （P〈0.05） and a significant difference was observed between the two groups. Conclusion： Male ages have a certain effect on sperm morphology and sperm DNA integrity and attention should be paid to this factor during clinical practice. |
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