彩色多普勒超声测定胎儿大脑中动脉血流速度与围产儿预后的相关性研究

目的探讨应用彩色多普勒超声测定孕晚期胎儿大脑中动脉（MCA）血流参数与围产儿预后的相关性。方法通过运用彩色多普勒超声测定晚孕期胎儿MCA血流速度，并对胎儿预后进行随访观察。结果异常组胎儿MCA—ED显著高于正常组胎儿、MCA—PI、MCA—RI、MCA—S／D均显著低于正常组胎儿；以MCA—ED大于其正常值2个标准差、MCA—PI〈1．4、MCA—RI〈0．6、MCA—S／D值〈4．0为血流异常，预测胎儿预后不良的敏感性及特异性分别为26．39％和97．33％、62．50％和56．00％、12．50％和98．67％、65．28％和52．00％。结论彩色多普勒超声测定胎儿大脑中动脉血速度对预测围产儿预后具有一定的临床价值。

Study on the association of the pregnancy prognosis with the fetal middle cerebral artery blood flow velocity by color Doppler ultrasonography

Objective： To study the association of pregnancy prognosis and Middle Cerebral Artery （MCA） blood flow parameters by using Color Doppler Ultrasonography in the late pregnancy period. Methods： Using Color Doppler Ultrasonography to examine fetal MCA flow in the late pregnancy period, and followed a close observation on all fetuses pregnancy prognosis. Results： Compare with the good group, MCA - EDV of the abnormal group increased significantly, MCA - PI, MCA - RI, MCA - S/D of the abnormal group de-creased significantly, with the difference significant （P 〈0. 001 ）. Provided MCA - EDV 〉2SD, MCA - PI 〈 1.4, MCA - RI 〈0. 6, MCA - S/D 〈 4. 0 as abnormal condition, the sensitivity and specificity of predicting fetal poor prognosisg are respectively 35.00% and 98. 33%, 70. 00% and 66. 67%, 15.00% and 98. 33%, 71.67% and 61.67%. Conclution： There is clinical value for using Col-or Doppler to monitor fetal MCA flow velocity as to predict fetal pregnancy prognosis.