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Mandibular augmentation in dogs with hydroxylapatite combined with demineralized bone
Authors:M S Block  J N Kent  R C Ardoin  W Davenport
Institution:1. Clinic of Farm Animals, Faculty of Veterinary Medicine, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece;2. Laboratory of Animal Husbandry, Faculty of Veterinary Medicine, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece;3. Diagnostic Laboratory, Faculty of Veterinary Medicine, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece;1. Laboratory of Fundamental Oncology, National Cancer Center Research Institute, Chuo-ku, Tokyo 103-0045, Japan;2. Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital of Wuerzburg, Oberduerrbacher Strasse 6, Wuerzburg 97080, Germany;3. London Vet Specialists, 56 Belsize Lane, London NW3 5AR, United Kingdom;4. Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy;5. Endocrinology Unit, Department of Clinical and Molecular Medicine, Sant''Andrea Hospital, Sapienza University of Rome, Via di Grottarossa, 1035/1039, Rome 00189, Italy;6. I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Martinstrasse 52, Hamburg 20246, Germany
Abstract:This study investigates the tissue response in dogs to mandibular augmentation with hydroxylapatite (HA) combined with demineralized bone. Thirty mongrel dogs underwent ridge augmentation with 3 ml of HA alone (HAO), HA combined with autogenous bone (HAB), or HA combined with demineralized bone (HAD). Bone was not found in the HAO augmented ridges through 52 weeks; bone was found in the HAB augmented ridges by 12 weeks, and the HAD augmented ridges had bone formation after 26 weeks. This study demonstrates that demineralized bone can induce osteogenesis within the HA augmented dog ridge, but it is delayed when compared to HAB augmentations.
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