152例老年大肠癌临床病理学特征与预后

目的探讨老年人大肠癌的临床病理学特征与预后。方法总结1993年7月-2000年12月间收治的65岁以上老年人大肠癌152例，分析其临床特点、病理学特征和生存率。结果152例老年人大肠癌中，合并其他疾病者101例（66．5％1；Dukes分期：B、C期116例（76．3％）。病理类型：腺癌131例（86．2％），其中高、中分化腺癌83例，低分化腺癌48例；黏液腺癌13例（8．5％）；印戒细胞癌3例（2．0％）；息肉恶变5例（3．3％）；合并大肠息肉25例（16,4哟；多原发性大肠癌2例（1．3％）；术后1年生存率90．2％，3年生存率76．8％，5年生存率55．4％。结论目前老年大肠癌发病率逐渐增高，临床分期以进展期为主，病理类型主要为高、中分化腺癌，手术根治率高，预后较好，但应注意合并大肠息肉及多发原发性大肠癌的发生。

Clinical pathological features in 152 cases of elderly patients with colorectal cancer

[Objective] To discuss the clinical pathological feature and prognosis in 152 cases of elderly patients with colorectal cancer.[Methods] We analyzed the clinical pathological feature and survival rate of colorectal cancer patients whose age were 65 years or above from July 1993 to December 2000.[Results] Comorbidities were 101 cases in 152 cases elderly patients.Dukes stages B and C were noted in 116 cases(76.3%).The proportion of adenocarcinoms was 86.2%(131/152),Mucinous carcinoma was 8.5%(13/152),signet-ring cell carcinoma was 2.0%(3/152)and polypi canceration was 3.3%(5/152).The proportion of accompanied polypi was 16.4%(25/152)and multiple primary colorectal cancer was 1.3%(2/152).The 1-year survival rate was 90.2%,the 3-year survival rate was 76.8% and the 5-year survival rate was 55.4%.[Conlusion] At present elderly patients with colorectal cancer have a high Morbidity,many comorbidities,a high proportion of advenced stage and moderately and well-differentiated adencarcinoma in pathological classification,a high complete resection rate and good prognosis.But accompanied polypi and multiple primary colorectal carcinoma should be attentioned.