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Endothelial cells lining polyester fabric express pro-coagulant phenotypein vitro |
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| Authors: | Dr M Rémy R Bareille F Villars F Rouais A Gorodkov L Bordenave |
| Institution: | (1) INSERM U 443, Université Victor Segalen Boreaux 2, 146, Rue Léo Saignat, 33076 Bordeaux Cedex, France;(2) Institut Bakoulev, Scientific Center of Cardiovascular Surgery 8, Leninsky Prospect, 117049 Moscow, Russia |
| Abstract: | The paper deals with the in vitro assessment of endothelial cell (EC) phenotype covering an albumin- and chitosan-coated polyester fabric and shows that resting ECs express a pro-coagulant phenotype by releasing a high von Willebrand factor level and expressing low thrombomodulin surface activity, despite maintaining an adequate response to stimulating agents. |
| Keywords: | Endothelial cell polyester fabric von Willebrand factor Thrombomodulin |
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