化脓性眼内炎治疗失败原因分析

目的 探讨化脓性眼内炎治疗失败原因。方法 化脓性眼内炎６３例，６例采用传统的常规治疗，２３例单纯玻璃体腔内注药，３４例采用玻璃体腔注药及玻璃体切除术。结果 显效１３例占２０．６％，有效１５例占２３．８％，无效３５例占５５．６％。结论 未能早期诊断并在４８小时内玻璃体腔注射抗生素及未切除玻璃体是眼内炎治疗失败的重要原因。药物敏感试验尚无结论者可选用头孢唑啉钠２．２５ｍｇ玻璃体腔注射。

Analysis of the causes of the unsuccessful treatment of endophthalmitis

Objective To analyse the causes of the unsuccessful treatment of endophthalmitis and the effective methods in the treatment of endophthalmitis. Methods Treatment of 63 cases of endophthalmitis. Six cases were treated by traditional method,23 cases had intravitreal injection and 34 cases had intravitreal injection combined with vitrectomy. Results The visual acuity in 13 cases were more than 0.05 (20.6%),light percent (LP) to 0.05 in 15 cases (23.8%) and 35 cases lost visual acuity or eye balls. Conalusion Delay of diagnosis and intravitreal injection of antibiotic in 48 hours are the important factors cause the unsuccessful treatment of the endophthalmitis. Intravitreal injection of 2.25mg Cefazolinu Natricum should be of choice before the sentitivity antibiotics are known.