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Nivolumab plus low-dose ipilimumab in previously treated patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: 4-year follow-up from CheckMate 142
Affiliation:1. Sorbonne Université and Department of Medical Oncology, Hôpital Saint Antoine, Assistance Publique Hôpitaux de Paris, Paris, France;2. Equipe Inserm Instabilité des Microsatellites et Cancer, UMRS 938-Centre de Recherche Saint-Antoine, Paris, France;3. Veneto Institute of Oncology IOV-IRCCS, Padua, Italy;4. Medical Oncology, Westmead Hospital, Sydney, Australia;5. Department of Medical Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, USA;6. Oncology Unit, University Hospital of Modena, Modena, Italy;7. Department of Medical Oncology, Candiolo Cancer Institute, FPO IRCCS, Candiolo, Italy;8. Department of Oncology, University of Torino, Candiolo, Italy;9. Department of Medicine, Duke University Medical Center, Durham, USA;10. Department of Gastroenterology/Digestive Oncology, University Hospitals Gasthuisberg/Leuven and KU Leuven, Leuven, Belgium;11. Medical Oncology, St Vincent’s University Hospital and Cancer Trials Ireland, Dublin, Ireland;12. Medical Oncology, Tasman Oncology Research, Ltd., Southport, Australia;13. Department of Oncology, Cross Cancer Institute and University of Alberta, Edmonton, Canada;14. Department of Medical Oncology, Institut Jules Bordet, Brussels, Belgium;15. Department of Medical Oncology, Universitair Ziekenhuis Brussel, Brussels, Belgium;16. Oncology Clinical Development, Bristol Myers Squibb, Princeton, USA;17. Oncology Medical Affairs, Global Biometrics and Data Sciences, Bristol Myers Squibb, Princeton, USA;18. Clinical Biomarkers, Translational Medicine, Bristol Myers Squibb, Princeton, USA;19. Worldwide Health Economics and Outcomes Research, Bristol Myers Squibb, Princeton, USA;20. Department of Gastrointestinal Medical Oncology, MD Anderson Cancer Center, Houston, USA
Abstract:
Keywords:nivolumab  ipilimumab  immune checkpoint inhibitor  colorectal cancer  metastatic  MSI-H/dMMR
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