Echocardiographic assessment of atrial function in patients with hypertrophic cardiomyopathy with and without paroxysmal atrial fibrillation |
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Institution: | 1. Instituto Dante Pazzanese de Cardiologia, São Paulo, Brazil;2. DASA Diagnostic Group, São Paulo, Brazil;3. Instituto do Coração (INCOR) do Hospital das Cínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP);4. Grupo Fleury Medicina e Saúde, São Paulo |
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Abstract: | Introduction and objectivesHypertrophic cardiomyopathy (HCM) is accompanied by pathophysiological changes that predispose to the development of atrial fibrillation (AF). This arrhythmia impacts negatively on the morbidity, mortality and quality of life of these patients. Our objective was to evaluate the behavior of left atrial function, by means of atrial strain (derived from speckle tracking) and volumetric analysis by three-dimensional echocardiography, in patients with HCM with paroxysmal AF.MethodWe analysed left atrial function in 53 patients with HCM, 25 of whom were paroxysmal AF carriers (mean age 61.7±9.9 years; 56% female) compared with 28 members of the control group (mean age 60.5±10 years; 53.6% female) who were matched especially for sex, age and other demographic data.ResultsIt was observed that patients with HCM and a history of paroxysmal AF had lower left atrial emptying fractions than individuals in the control group; and the active atrial emptying fraction was a factor independently associated with the presence of this arrhythmia (p=0.018; odds ratio=0.93). Moreover, we found a significant reduction of the left atrial strain in all its components in the total sample of patients, with no difference between the groups.ConclusionsMeasurements of atrial emptying fractions by three-dimensional echocardiography allowed differentiating patients with HCM with and without paroxysmal AF. |
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Keywords: | Hypertrophic cardiomyopathy Atrial fibrillation Three-dimensional echocardiography Atrial function Miocardiopatia hipertrófica Fibrilhação auricular Ecocardiografia tridimensional Função auricular |
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