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Neoadjuvant afatinib with paclitaxel for triple-negative breast cancer and the molecular characteristics in responders and non-responders
Affiliation:1. Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan;2. Institute of Medical Genomics and Proteomics, College of Medicine, National Taiwan University, Taipei, Taiwan;3. Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan;4. Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan;5. Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan;6. Department of Surgery, Chung Kang Branch, Cheng Ching Hospital, Taichung, Taiwan;7. Hematology and Oncology, Department of Internal Medicine, Tri-service General Hospital, Taipei, Taiwan;8. Department of Surgery, China Medical University Hospital, Taichung, Taiwan;9. Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan;10. Boehringer Ingelheim Taiwan, Taipei, Taiwan;11. ACT Genomics, Taipei, Taiwan;12. Department of Medical Oncology, National Taiwan University Hospital, Taipei, Taiwan;13. Department of Surgery, College of Medicine, National Taiwan University, Taipei, Taiwan
Abstract:
Keywords:Triple-negative breast cancer  afatinib  Neoadjuvant  PI3K  Homologous recombination  TNBC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  triple-negative breast cancer: OS  overall survival: pCR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  pathologic complete response: EGFR  epidermal growth factor receptor: PD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  progressive disease: PR  partial response: SD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  stable disease
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