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Evolving Role of Circulating Tumor DNA and Emerging Targeted Therapy in Colorectal Cancer
Affiliation:1. Section of Hematology/Oncology, West Virginia University School of Medicine, 1 Medical Center Drive, Morgantown, WV 26506, USA;2. Harvard Medical School, Massachusetts General Hospital Cancer Center, Tucker Gosnell Center for Gastrointestinal Malignancies, Termeer Center for Targeted Therapies, Boston, MA 02114, USA;1. Colorectal Unit, Department of Surgery, Complejo Asistencial Doctor Sótero del Río, Santiago, RM, Chile;2. Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue | SR-201, New York, NY 10065, USA;1. UCLA Department of Internal Medicine, UCLA Health/ David Geffen School of Medicine, UCLA Medical Education Office, RRUCLA Medical Center, 757 Westwood Plaza, Suite 7501, Los Angeles, CA 90095, USA;2. Vatche and Tamar Manoukian Division of Digestive Diseases, Center for Health Sciences, 650 Charles E. Young Drive South, Suite A2-125, Los Angeles, CA 90095-6900, USA;3. Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA Kaiser Permanente Center for Health Equity, Jonsson Comprehensive Cancer Center, Center for Health Sciences, 650 Charles E. Young Drive South, Suite A2-125, Los Angeles, CA 90095-6900, USA;1. Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;2. Center for Surgery and Public Health, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;1. Division of Human Genetics, Biospecimen Research, Internal Medicine, The Ohio State University Comprehensive Cancer Center, 2012 Kenny Road, Room 257, Columbus, OH 43221, USA;2. Division of Colorectal Surgery, Division of Colon & Rectal Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA;3. Internal Medicine, The Ohio State University Comprehensive Cancer Center, 2012 Kenny Road, Room 255, Columbus, OH 43221, USA;4. Division of Gastroenterology, Hepatology & Nutrition, The Ohio State University Wexner Medical Center, 395 W 12th Avenue, Second Floor, Columbus, OH 43210, USA
Abstract:
Keywords:Circulating tumor DNA  Response prediction  Minimal residual disease  Targeted therapy  Gene fusions  Precision medicine
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