23例肝肺综合征临床分析

探讨肝肺综合征(HPS)的临床特点和预后。67例肝硬化患者均应用血气分析仪测定其动脉血氧分压(PaO2),其中Ch ild-Pugh分级A级30例,B级22例,C级15例。67例肝硬化患者中23例合并HPS,发病率为34.3%。其发病率与Ch ild-Pugh分级有关,与A级比较C级HPS,发病率显著增高(P<0.05);门静脉增宽与不宽者、胃底食管静脉曲张与未发现曲张者、有蜘蛛痣与无蜘蛛痣者分别合并有HPS,两者比较均差异有显著性(P<0.05)。23例HPS患者中7例死亡,HPS均不是直接死亡原因。有门脉高压、蜘蛛痣时提示HPS的存在。早期诊断和治疗有助于缓解低氧血症,改善预后。

Clinical analysis of 23cases hepatopulmonary syndrome

To study the clinical characteristic and prognosis of hepatopulmonary syndrome(HPS).The partial pressure of the arterial oxygen(PaO_2) in 67 cases with live cirrhosis were examined by automatic blood gas analyzer.Of them 30 were classified as Child-Pugh A,22 Child-Pugh B and 15 Child-Pugh C.23 cases of HPS confirmed by clinical data were reviewed.23 cases of HPS in 67 cases with live cirrhosis,the incidence of HPS is 34.3%.The incidence of HPS is related with Child-Pugh grade.Compared the Child-Pugh C with Child-Pugh A,the incidence of HPS is significant(P<0.05).Compared HPS that have different portal vein bore, have esophageal and gastric varices or not,have spider nevus or not,the incidence is significant(P<0.05).7 cases in 23 cases HPS has died.HPS is not direct dead cause.The constellation of clinical findings of portal hypertension,spider nevus is strongly suggestive of HPS.The initial diagnosis and treatment HPS are conducive to relieve hypoxemia and improve patient prognosis.