| 肺泡压升高对狗右心室收缩性能的影响 |
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| 引用本文： | 杨鹏麟,徐力辛,胡良周,蔡孔长,蒋仲荪,徐正惠.肺泡压升高对狗右心室收缩性能的影响[J].温州医学院学报,1989(3). |
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| 作者姓名： | 杨鹏麟 徐力辛 胡良周 蔡孔长 蒋仲荪 徐正惠 |
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| 作者单位： | 温州医学院肺心病研究室
(杨鹏麟，徐力辛，胡良周，蔡孔长，蒋仲荪)，温州医学院肺心病研究室(徐正惠) |
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| 摘 要： | 用肺泡加压法单纯增加狗的右心室后负荷发现,当肺泡压轻度增加时,右心室收缩力增加,而左心室收缩力、流量、左房压和舒张期冠脉灌注压差不变;当肺泡压升至1.5kPa时,右心室收缩力开始下降,左心室收缩力下降更明显,流量、舒张期冠脉灌注压差下降和右房压增加。故本实验提示:①右心室后负荷增加时,左心室并没有进一步加强心室间的偶联作用帮助右心室克服后负荷。②右心室收缩性能对血流动力学的稳定有重要意义,当其不耐后负荷时会引起血流动力学的紊乱。
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| 关 键 词： | 肺泡压 右心室 收缩性能 冠状灌注压 |
INFLUENCE OF ELEVATED ALVEOLAR PRESSURE ON RIGHT VENTRICULAR CONTRACTILE PROPERTY IN DOG |
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| Yang Penglin,et al.INFLUENCE OF ELEVATED ALVEOLAR PRESSURE ON RIGHT VENTRICULAR CONTRACTILE PROPERTY IN DOG[J].Journal of Wenzhou Medical College,1989(3). |
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| Authors: | Yang Penglin |
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| Institution: | Cor Pulmonale Research Laboratory |
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| Abstract: | When right ventricular afterload is increased in six open thoracic dogs, it is found that when alveolar pressure is elevated to 1.0 KPa or less, RV dp/dt rises and LV dp/dt is unchanged; that when the pressure is elevated to 1.5 KPa, RV dp/dt begins to lower and LV dp/dt is significantely decreased. The disorder of blood dynamics appeares. The experiment suggests( 1 )when right ventricular afterload is increased, left ventricle do not help right ventricle to overcome the afterload by the double action of two ventricles; (2) right ventricular contractile property be of importance in sustainig the steadiness of blood dynamics, and if it cannot ovecome the afterload, disorder of blood dynamics will be its result. |
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| Keywords: | alveolar pressure right ventricle contractile property coronary perfussion pressure |
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