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Haemophilus influenzae type b serology in childhood leukaemia: a case-control study
Authors:Groves F D  Sinha D  Kayhty H  Goedert J J  Levine P H
Affiliation:Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA.
Abstract:Antibody to Haemophilus influenzae type b (Hib) polysaccharide (PRP) was measured in 42 children with acute lymphoblastic leukaemia (ALL) and 42 non-leukaemic hospital controls. Modelling anti-PRP concentrations as a function of age revealed that the slopes of the trend lines differed significantly between cases and controls (P = 0.05); anti-PRP concentrations were lower among younger cases, and higher among older cases, than among controls of the same ages.
Keywords:leukaemia   child   serology   Haemophilus influenzae type b   case–control study
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