Haemophilus influenzae type b serology in childhood leukaemia: a case-control study |
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Authors: | Groves F D Sinha D Kayhty H Goedert J J Levine P H |
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Affiliation: | Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA. |
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Abstract: | Antibody to Haemophilus influenzae type b (Hib) polysaccharide (PRP) was measured in 42 children with acute lymphoblastic leukaemia (ALL) and 42 non-leukaemic hospital controls. Modelling anti-PRP concentrations as a function of age revealed that the slopes of the trend lines differed significantly between cases and controls (P = 0.05); anti-PRP concentrations were lower among younger cases, and higher among older cases, than among controls of the same ages. |
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Keywords: | leukaemia child serology Haemophilus influenzae type b case–control study |
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