Influence of nicotine on simulator flight performance in non-smokers |
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Authors: | M S Mumenthaler Joy L Taylor Ruth O’Hara Jerome A Yesavage |
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Institution: | (1) Stanford University, School of Medicine, Department of Psychiatry, C301, Stanford, CA 94305–5550, USA, US;(2) Department of Veterans Affairs Health Care System, Palo Alto, California, USA, US |
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Abstract: | In a placebo-controlled study, we investigated the influence of nicotine on late-day aviation performance in 15 non-smoking
subjects. In a within-subjects design, subjects were tested on 2 days, each lasting 8 h and consisting of three 75-min simulator
flights (late-afternoon practice, evening test, night test). Prior to each test, subjects received either nicotine polacrilex
2 mg or placebo gum. As expected, overall performance was significantly better after nicotine, compared to placebo (P < 0.01). Post-hoc analysis of individual flight tasks showed that nicotine improved scores on approach to landing, a task
which appears to require sustained attention. We conclude that nicotine may improve late-day flight performance in non-smoking
aviators.
Received: 15 September 1997/Final version: 11 March 1998 |
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Keywords: | Nicotine Cognition Psychomotor performance Task performance and analysis Aerospace medicine Attention Workload Chewing gum Non-smoker |
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