Tubular Carcinoma of the Breast: A Histologic Subtype Indicative of Breast-Conserving Therapy |
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Authors: | Keisei Anan Shoshu Mitsuyama Keiyoshi Tamae Kazuyoshi Nishihara Toshimitsu Iwashita Yuji Abe Takaaki Ihara Shousaku Nakahara Fujio Katsumoto Shigeaki Takeda Satoshi Toyoshima |
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Institution: | (1) Departments of Surgery and,;(2) Pathology, Kitakyushu Municipal Medical Center, Kokurakita-ku, 2-1-1 Bashaku, Kitakyushu 802-0077, Japan, JP |
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Abstract: | We reviewed the clinical and pathologic features of pure tubular carcinoma of the breast with particular emphasis on the
reported risk factors associated with local recurrences and survival following breast-conserving therapy. Of 1653 cases of
invasive breast cancer, 12 (0.7%) were identified as pure tubular carcinoma. Clinical/pathologic features of pure tubular
carcinoma were compared with those of T1 invasive carcinoma of all other histologic types (T1 IC). Of the 12 patients with
pure tubular carcinoma (median tumor diameter 1.4 cm; range 0.5–3.0 cm), a multicentric association was identified in one
patient while a multifocal association was seen in two. One patient had nodal metastatic disease out of the ten who underwent
axillary dissection. No lymphatic vessel invasion was identified in any tumors (P < 0.1 vs T1 IC). In addition, extensive intraductal spread was not present in any tumors (P < 0.05 vs T1 IC). This study shows that patients with pure tubular carcinoma are appropriate candidates for breast-conserving
therapy based on the clinical/pathologic features. When a multifocal association is suspected preoperatively, either a wide
local excision or a quadrantectomy which includes other lesions is thus recommended.
Received: January 21, 2000 / Accepted: July 25, 2000 |
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Keywords: | Margin Extensive intraductal carcinoma Irradiation Tubular carcinoma Breast |
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