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美降之与立平脂治疗原发性高脂血症的临床观察
引用本文:杨菊贤,黄震华.美降之与立平脂治疗原发性高脂血症的临床观察[J].现代诊断与治疗,1994,5(6):336-338.
作者姓名:杨菊贤  黄震华
作者单位:上海第二医科大学附属第九人民医院心内科
摘    要:报道美降之与立平脂治疗原发性高脂血症各30例的效果,结果显示服用美降之8周后,降低血清胆固醇为86.87%,降低甘油三酯(Tg)为53.84%。平均降低Ch20.62%,LDL-C9.78%,APO-B10.74%,Ch/HDL-C29.70%,平均升高HDL-C11.91%,APO-A12.57%,APO-A/APO-B24.51%。服用立平脂8周后降低Tg的作用显著,总有效率为84.61%,除Tg外,其余参数的效果均不如美降之组。

关 键 词:美降之,立平脂,胆固醇,甘油三脂,APO-A/,APO-B,Ch/HDL-C

Clinical Observation of Lovastatin and Lipanthyl in Treatment of Patiens withPrimary Hyperlipidemia
Yang Juxian,Huang Zhenbua,Wu Shiyao,Sheng Jing,Xu Jimin,Lu Lixiong.Clinical Observation of Lovastatin and Lipanthyl in Treatment of Patiens withPrimary Hyperlipidemia[J].Modern Diagnosis & Treatment,1994,5(6):336-338.
Authors:Yang Juxian  Huang Zhenbua  Wu Shiyao  Sheng Jing  Xu Jimin  Lu Lixiong
Abstract:This paper reports the efficacy of Lo-vastatin and Lipanthyl to treat 30 patients with pri-mary hyperlipidemia respectively. The resultsshowed that 8 weeks after taking Lovastatin , theserum chlesterol(Ch)and triglyceride(Tg )level ofthe patients dropped 86.87%and 53.84%respective-ly ,and the average dropping ratio of Ch was 20.62%,LDL-C9.78%,APO-B10.74% and Ch/HDL29.70%respectively; The average elevation ratio ofHDL-C was 11.9%,APO-A12.5% and APO-A/APO-B24.51%. There was a significent dropping ofserum Tg level 8 weeks after taking Lipanthyl,andits total efficacy was 84.61%, however ,except forTg, other parameters of Lipanthyl had less efficacythan Lovastatin.
Keywords:Lovastatin Lipanthyl Cholesterol Triglyceride APO-A/APO-B Ch/HDL-C  
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