Dimethyl cathate: synthesis and pharmacological investigation |
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Authors: | M L Stein P Nencini |
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Affiliation: | Department of Pharmaceutical Studies, University of Rome La Sapienza, Italy. |
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Abstract: | Dimethyl cathate was synthesized through a reaction sequence starting from 3,4-pyridinedicarboxylic acid anhydride, and hydrolyzed to the not yet described cathic acid. Pharmacological screening procedures only showed a protection against the convulsive effect of pentylenetetrazol. |
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