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紫杉醇联合卡培他滨治疗老年晚期胃癌21例临床疗效观察
引用本文:程华.紫杉醇联合卡培他滨治疗老年晚期胃癌21例临床疗效观察[J].按摩与导引,2010(3):74-75.
作者姓名:程华
作者单位:江西省广丰县人民医院,广丰334600
摘    要:目的:评价紫杉醇(Taxol)联合卡培他滨(Xeloda)治疗老年晚期胃癌的临床疗效和毒副反应。方法:对病理诊断的25例老年晚期胃癌患者,采用紫杉醇联合卡培他滨方案治疗:紫杉醇75mg/m2,静脉滴注3h,每周1次,连用2周;卡培他滨每日2500mg/m2,连用14天l以上化疗方案每3周重复,2个周期后评定疗效。结果:可评价疗效者21例,无完全缓解(CR),部分缓解(PR)10例(47.6%),稳定(SD)5例(23.8%),进展(PD)6例(28.6%),总有效率(CR+PR)为47.6%。中位进展期5~6个月,中位生存期8~9个月。主要毒副反应:骨髓抑制18例(85.7%),脱发15倒(71.4%),腹泻10例(47.6%),肌肉关节痛5例(23.8%)等。所有Ⅲ度毒副反应发生6例(28.5%),无治疗相关性死亡。结论:紫杉醇联合卡培他滨治疗老年晚期胃癌患者有效率较高,毒副反应可耐受,是老年晚期胃癌较理想的化疗方案。

关 键 词:胃肿瘤  紫杉醇  卡培他滨  药物治疗

The taxus mellow union card cultivates his shore treatment old age later period stomach cancer 21 examples clinical curative effect observation
Cheng Hua.The taxus mellow union card cultivates his shore treatment old age later period stomach cancer 21 examples clinical curative effect observation[J].Chinese Manipulation & Qi Gong Therapy,2010(3):74-75.
Authors:Cheng Hua
Abstract:Along with the effective form application like patient's choice, the contrast medium type and the dosage control, the correct hydration and stop using other kidneys toxically and so on, the contrast medium nephrosis (CIN) disease incidence rate drop gradually, but present CIN still was the medical source impatient kidney function failure (ARF) third cause of disease. This article summarizes as follows to the contrast medium nephro- sis dangerous factor.
Keywords:The contrast medium Nephrosis Dangerous factor Research progress
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