Acute venous catheterization for integrated plasma sample collection in monkey |
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Authors: | Mark P. Bree Nancy K. Mello Kathy L. Harvey Susan A. Webb |
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Affiliation: | Alcohol and Drug Abuse Research Center McLean Hospital-Harvard Medical School, Belmont, MA 02178, USA |
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Abstract: | A method is described which permits acute percutaneous venous catheterization for continuous blood collection over a period of several hours. This procedure can also be used for collection of repeated bolus samples without additional venipunctures. Potential applications include collection of integrated plasma samples for neuroendocrine analysis of discrete plasma samples for pharmacokinetic studies. |
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Keywords: | Acute venous catheterization Primates Blood sample collection Integrated plasma sampling |
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