| 枳木具子水提取液对四氯化碳致小鼠肝损伤的保护作用 |
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| 引用本文： | 嵇扬,陆红. 枳木具子水提取液对四氯化碳致小鼠肝损伤的保护作用[J]. 时珍国医国药, 2002, 13(6): 327-328 |
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| 作者姓名： | 嵇扬 陆红 |
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| 作者单位： | 1. 中国人民解放军总后勤部卫生部药品仪器检验所,北京,100071
2. 中国人民解放军空军沈阳医院,辽宁,沈阳,110005 |
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| 摘 要： | 目的：了解枳Ju子水提取液对四氯化碳致小鼠肝损伤的保护作用。方法：在小鼠灌胃给予药液后7d，腹腔注射四氯化碳，16h后眼眶采血测定谷丙转氨酶（ALT）、谷草转氨酶（AST）、乳酸脱氢酶（LDH）、胆固醇（CH）、甘油三酯（TG）等生化指标。通过比较药物组是否明显降低四氯化碳所致的生化指标异常升高，评价药物的保护作用。结果：枳Ju子水提取液明显降低四氯化碳所致的谷丙转氨酶、谷草转氨酶、乳酸脱苯氢酶是生化指标的异常升高。结论：枳Ju子水提取液对四氯化碳致小鼠肝损伤具有保护作用。
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| 关 键 词： | 枳Ju子 四氯化碳 保肝作用 中药 |
| 文章编号： | 1008-0805(2002)06-0327-01 |
| 修稿时间： | 2001-12-28 |
Protective Effects of the wter Extract form Hovenia dulcis Thunb. on CCl4-induced Experimental Hepatic Injury |
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| JI Yang ,LU Hong. Protective Effects of the wter Extract form Hovenia dulcis Thunb. on CCl4-induced Experimental Hepatic Injury[J]. Lishizhen Medicine and Materia Medica Research, 2002, 13(6): 327-328 |
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| Authors: | JI Yang LU Hong |
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| Affiliation: | JI Yang 1,LU Hong 2 |
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| Abstract: | Objective:To investigate the protective effects of the water extract from Hovenia dulcis Thunb. (HDT) on carbon tetracholride (CCl 4) induced experimental hepatic injury in mice. Methods:The model of hepatic injury was induced by CCl 4. The biochemical indexes of serum ALT, AST, LDH, CH, TG were determined. Results:HDT significantly inhibited the rising of serum ALT, AST, LDH induced by CCl 4. Conclusion:HDT had significant protective effects on CCl 4 induced experimental hepatic injury. |
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| Keywords: | Hovenia dulcis Thunb. CCl 4 Protective effects on hepatic injury |
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