| HBV基因型与中国人群临床表现相关性研究 |
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| 引用本文： | 赖翼,张帅,徐锐,刘阳. HBV基因型与中国人群临床表现相关性研究[J]. 成都医学院学报, 2013, 8(1): 39-42 |
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| 作者姓名： | 赖翼 张帅 徐锐 刘阳 |
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| 作者单位： | 赖翼 (成都医学院,成都,610500)；张帅 (成都医学院,成都,610500)；徐锐 (成都医学院,成都,610500)； 刘阳 (成都医学院,成都,610500)； |
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| 基金项目： | 四川省教育厅资助项目（NO：11ZB169,12ZB205） |
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| 摘 要： | 乙肝病毒（Hepatitis B Virus，HBV）感染是目前世界上最主要的感染性疾病之一。近年来，关于HBV基因型与疾病进程、HBeAg阳性率及HBV DNA水平相关性的研究还存在分歧。本文综合分析了2003年至2011年发表的20余篇探讨HBV基因型与疾病进程、HBeAg阳性率及HBV DNA水平相关性的文献结果，其中HBV/B型感染者共1745例，HBV/C型感染者共3114例。结果显示，C型感染者与B型相比，更易发展为肝硬化、肝癌与重症肝炎；C型感染者HBeAg阳性率与HBV DNA水平均显著高于B型感染者。
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| 关 键 词： | 乙肝病毒 基因型 |
The Relationship of HBV Genotype and Clinical Manifestation in Chinese People |
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| LAI Yi,ZHANG Shuai,XU Rui,LIU Yang. The Relationship of HBV Genotype and Clinical Manifestation in Chinese People[J]. Journal of Chengdu Medical College, 2013, 8(1): 39-42 |
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| Authors: | LAI Yi ZHANG Shuai XU Rui LIU Yang |
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| Affiliation: | (Chengdu Medical College ,Chengdu 610500 ,China) |
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| Abstract: | Hepatitis B Virus infection is one of the serious infective diseases in the worlde. There is a dispute on the relationship of HBV genotype and disease proceeding, HBeAg positive rate, and HBV DNA concentration. This paper analyzed more than twenty literatures on the relationship of HBV genotype and disease proceeding, HBeAg positive rate and HBV DNA concentration in 1 745 patients infected by HBV/B and 3 114 patients infected by HBV/C, Patients infected by HBV/C were more hepatic failure. HBeAg positive rate and HBV DNA HBV/B infective patients. susceptive with liver cirrhosis, hepatic cancer and fulminant concentration were higher in HBV/C infective patients than |
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| Keywords: | Hepatitis B Virus Genotype |
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