| 我国武汉地区工人和德国工人冠心病危险因素的调查和5年随访 |
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| 引用本文： | 邓耀祖,冯宗忱,戴闺柱,贺涵贞,沈凌汛,任平,刘幼文,王祥,章洁,王开富,郭和平,曾金华,R.Bernhardt,G.Schettler.我国武汉地区工人和德国工人冠心病危险因素的调查和5年随访[J].华中科技大学学报(医学版),1993(6). |
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| 作者姓名： | 邓耀祖 冯宗忱 戴闺柱 贺涵贞 沈凌汛 任平 刘幼文 王祥 章洁 王开富 郭和平 曾金华 R.Bernhardt G.Schettler |
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| 作者单位： | 同济医科大学基础医学院生物化学教研室，同济医科大学基础医学院生物化学教研室，同济医科大学心血管疾病研究所，同济医科大学公共卫生学院劳动卫生学教研室，同济医科大学公共卫生学院劳动卫生学教研室，同济医科大学基础医学院生物化学教研室，同济医科大学心血管疾病研究所，同济医科大学心血管疾病研究所，同济医科大学基础医学院生物化学教研室，同济医科大学基础医学院生物化学教研室，同济医科大学心血管疾病研究所，同济医科大学基础医学院生物化学教研室，德国海德堡科学院地缘医学研究所，德国海德堡科学院地缘医学研究所 武汉 430030，武汉 430030，武汉 430022，武汉 430030，武汉 430030，武汉 430030，武汉 430022，武汉 430022，武汉 430030，武汉 430030，武汉 430022，武汉 430030，海德堡 D-6900，海德堡 D-6900 |
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| 摘 要： | 中国工人低密度脂蛋白胆固醇(LDL-C)、极低密度脂蛋白胆固醇(VLDL-C)和载脂蛋白(apo)B分别为 2.46、0.28 mmol/L和 0.79 g/L,明显低于德国工人(分别为 3.75、0.62 mmol/L、1.21 g/L.P均<0.01)。两国工人高密度脂蛋白胆固醇(HDL-C)无显著性差异。在德国工人中辨别冠心病的敏感指标为甘油三酯(TG)、LDL-C升高,HDL-C降低,LDL-C/HDL-C 比值升高和高血压,抽烟等危险因素。在中国工人中仅为HDL-C降低、LDL-C/HDL-C 比值升高和高血压。德国工人心肌梗塞年发病率为中国工人的4.7倍,心肌梗塞死亡率占总死亡率的23％,中国工人约占9％。德国工人摄入的动物性脂肪明显多于中国人,摄入胆固醇的量为中国工人的3倍。
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| 关 键 词： | 冠心病 血脂 危险因素 心肌梗塞 随访研究 |
A Comparative Study of Coronary Risk Factors and Five-year Follow-up Observations in Chinese and German Workers |
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| Deng Yaozu,Feng Zongchen,Dai Guizhu et al.A Comparative Study of Coronary Risk Factors and Five-year Follow-up Observations in Chinese and German Workers[J].Journal of Huazhong University of Science and Technology(Health Sciences),1993(6). |
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| Authors: | Deng Yaozu Feng Zongchen Dai Guizhu |
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| Institution: | Deng Yaozu,Feng Zongchen,Dai Guizhu et alDepartment of Biochemistry,Tongji Medical University,Wuhan 430030Institute of Cardiovascular Diseases,Tongji Medical University,Wuhan 430022 |
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| Abstract: | The LDL-C, VLDL-C, and apoprotein B were significantly lower in the Chinese workers than in the German (2. 46 versus 3. 75 mmol/L, 0. 28 versus 0. 62 mmol/L, and 0. 79 versus 1. 21 g/L, respectively). The HDL-C were found to be within the same range in both Chinese and German workers. In the German group, high TC, LDL-C, high LDL-C/HDL-C ratio, hypertension and smoking are the most significant factors for coronary heart disease and myocardial infarction, while in the Chinese group, the main risk factors are low HDL-C, high LDL-C/HDL-C ratio, hypertension and smoking. The incidence of myocardial infarction in the German group was found to be 4. 7 times higher than that in the Chinese group. The mortality of myocardial infarction in the German group accounts for about 23% of all deaths, whereas that in the Chinese group only 9%. The animal fat intake was higher in the German group than in the Chinese. The daily cholesterol intake in the Chinese group is only one-third of that usually consumed by the German group. |
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| Keywords: | coronary heart disease serum lipid risk factor myocardial infarction follow-up studies |
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