益气化痰消瘿法对桥本甲状腺炎患者血清甲状腺球蛋白抗体、甲状腺过氧化物酶抗体的影响

目的观察益气化痰消瘿法中药对桥本甲状腺炎血清中甲状腺球蛋白抗体（TGAb）、甲状腺过氧化物酶抗体（TPOAb）的影响。方法将60例桥本甲状腺炎患者随机分为治疗组30例和对照组30例。两组患者甲状腺功能均经西药控制在正常范围;治疗组在此基础上加用益气化痰消瘿中药治疗。结果在降低TGAb、TPOAb值方面,治疗组治疗前后自身比较及治疗组与对照组治疗后相互比较差异均有显著性意义（P〈0.05或P〈0.01）。在改善甲状腺肿大方面,治疗组疗效也具有显著性意义（P〈0.05）。结论中药治疗能有效降低甲状腺自身免疫性抗体指标,并且对甲状腺肿大有效。

Effect of Qi-Boosting Phlegm-Transforming and Goiter-Dispersing on Serum Thyroglobulin Antibody and Thyroperoxydase Antibody in Hashimoto's Thyroiditis Patients

Objective To observe the effect of qi-boosting phlegm-transforming and goiter-dispersing medicinals on thyroglobulin antibody (TGAb) and thyroperoxydase antibody (TPOAb) in Hashimoto's thyroiditis (HT) patients. Methods Totally 60 cases of HT were randomly and equally divided into treatment group and control group. Western medical treatment was conducted in control group, while qi-boosting phlegm-transforming and goiter-dispersing medicinals were added in treatment group. Results After treatment, TGAb and TPOAb decreased significantly in treatment group with significant differences between two groups(P<0.05 or P<0.01). Thyromegaly was significantly relieved in treatment group as well(P<0.05). Conclusion Chinese medicinals can down regulate the indexes of thyreoid autoimmune antibodies and have therapeutic effect on thyromegaly.