30例结直肠癌肺转移患者的临床特征及预后分析

 目的  探讨结直肠癌(colorectal cancer,CRC)肺转移手术治疗后的生存预后情况。  方法  回顾性分析复旦大学附属中山医院胸外科2008年1月至2013年12月期间30例CRC肺转移手术治疗患者的临床资料。分析CRC原发灶手术与肺转移灶手术间期(disease-free interval,DFI)、癌胚抗原(carcinoembryonic antigen,CEA)、肺转移灶个数对术后生存情况的影响。  结果  高水平CEA是患者预后不良的因素,而DFI与CRC肺转移的病灶个数等对患者术后生存时间影响相对较小。  结论  积极手术治疗CRC肺转移可取得良好的预后疗效。

Clinical features and prognostic analysis of 30 patients with pulmonary metastasis from colorectal cancer

Objective  To investigate the survival prognosis after the surgery of pulmonary metastasis from colorectal cancer (CRC).  Methods  Clinical data of 30 cases with postoperative pathologically proven pulmonary metastasis from CRC in Zhongshan Hospital, Fudan University between Jan., 2008 and Dec., 2013 were analyzed retrospectively. We evaluated the influences of disease-free interval (DFI) of CRC primary lesions surgery and pulmonary metastasis surgery, carcinoembryonic antigen (CEA) and the number of pulmonary metastasis on survival and prognosis.  Results   High level of CEA was an important factor for poor prognosis. DFI and the number of pulmonary metastasis were not significantly correlated with the patients’ survival.  Conclusions  Active surgery treatment for pulmonary metastasis from CRC do generate good prognosis.