| CD4+CD25+T细胞研究新进展 |
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| 引用本文： | 蒋启发,谢荣华.CD4+CD25+T细胞研究新进展[J].实用预防医学,2007,14(1):249-252. |
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| 作者姓名： | 蒋启发 谢荣华 |
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| 作者单位： | 湖南环境生物职业技术学院医学部,湖南,衡阳,421001 |
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| 摘 要： | CD4 CD25 T细胞是新近才被认识的一类免疫调节细胞,在胸腺中产生,主要发挥抑制性免疫调节功能,表达IL-10 mRNA,细胞表面表达IL-2受体a链(CD25),在维持机体内环境的稳定、抗感染免疫、抗肿瘤免疫、诱导移植耐受及自身免疫性疾病等方面发挥重要作用。
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| 关 键 词： | CD4 CD25 T细胞 免疫调节 免疫耐受 肿瘤免疫 |
| 文章编号： | 1006-3110（2007）01-0249-04 |
| 收稿时间： | 2006-12-05 |
| 修稿时间： | 2006年12月5日 |
Advances on Cell CD4+ CD25+ T Research |
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| JIANG Qi-fa,XIE Rong-hua.Advances on Cell CD4+ CD25+ T Research[J].Practical Preventive Medicine,2007,14(1):249-252. |
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| Authors: | JIANG Qi-fa XIE Rong-hua |
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| Institution: | Medical Department, Hunan Environment -Biological Polytechnic, Hengyang 421001, Hunan, China |
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| Abstract: | CD4~ CD25~ T is a newly recognized type of immune-regulation cells. It plays a essential role in the inhibitive immune-regulation functions and is produced from the thymus glands, with expressing IL-10mRNA and IL-2 receptor 'a chain' (CD25), on the cell surface. Functioning CD4~ CD25~ T cells play an important role in the maintenance of homeostasis, anti-infection, anti-tumor immunity, induction of transplantation-rejection and autoimmune diseases. |
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| Keywords: | CD4~ CD25~ T Immuno-regulation Immune-tolerance Tumor immunity |
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