泮托拉唑钠治疗急性上消化道出血21例

目的：观察泮托拉唑钠治疗急性上消化道出血的疗效及安全性。方法：将42例患分为2组，治疗组(泮托拉唑钠)2l例，静脉滴注泮托拉唑钠40mg，2次／d，疗程3—5d；对照组(奥美拉唑钠)2l例，静脉滴注奥美拉唑钠40mg，2次／d，疗程3-5d.结果：治疗3d后，泮托拉唑治疗组总有效率为94．4％，患疼痛、呕血、黑便等症状消失率分别为93．7％，100．0％和90.5％，与对照组比较疗效无显性差异，且治疗组用药期间未发现严重不良反应。结论：泮托拉唑治疗急性上消化道出血安全、有效。

Clinical Evaluation of Pantoprazole in the Treatment of Acute Upper Gastrointestinal Hemorrhage

Objective: To observe the effect of pantoprazole for therapy of acute upper gastrointestinal hemorrhage. Methods: 42 patients were randomly divided into two groups. The therapy group (n = 21) received pantoprazole 40 mg, iv, gtt, Bid, persisting for 3 - 5 d. The control group (n = 21) received omeprazole 40 mg, iv, gtt, Bid, persisting for 3 - 5 d. Results: After three days therapy, effective rate of therapy group was 94. 4% . The rate of pain, reject bleeding, black stool disappearance were 93.7% ,100. 0% and 90.5% respectively. No significant differences between the two groups were found ( P > 0. 05). There was no serious adverse drug reaetion during the therapy. Conclusion: Pantoprazole is an effective and safe drug in the treatment of acute upper gastrointestinal hemorrhage.