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我市2007年1451例药品不良反应报告分析
引用本文:何伟珍,应小飞,华俊彦. 我市2007年1451例药品不良反应报告分析[J]. 中国药房, 2008, 19(32): 2534-2536
作者姓名:何伟珍  应小飞  华俊彦
作者单位:浙江省丽水市中心医院
摘    要:目的:探讨我市药品不良反应(ADR)发生的特点及规律。方法:对我市2007年ADR监测中心收集到的1451例ADR报告分别从患者性别、年龄、给药途径、药品类别、ADR涉及器官或系统及主要临床表现等方面进行统计、分析。结果:在1451例ADR报告中,给药方式以静脉滴注为主(占72.16%);抗感染药引起的ADR最多,其中青霉素类、头孢菌素类、喹诺酮类是引起ADR的主要药物;累及的器官或系统以皮肤及其附件所占比例最大。结论:应加强合理用药监测,以减少和避免ADR的发生。

关 键 词:药品不良反应  合理用药  分析  监测

ADR Reports: Analysis of 1 451 Cases in Our City in 2007
HE Wei-zhen,YING Xiao-fei,HUA Jun-yan. ADR Reports: Analysis of 1 451 Cases in Our City in 2007[J]. China Pharmacy, 2008, 19(32): 2534-2536
Authors:HE Wei-zhen  YING Xiao-fei  HUA Jun-yan
Affiliation:(Zhejiang Lishui Central Hospital, Lishui 323000, China)
Abstract:OBJECTIVE:To discuss the characteristics and regularities of adverse drug reactions(ADR)occurring in our hospital.METHODS:A total of 1 451 ADR cases collected by ADR monitoring center in 2007 were analyzed statistically in respect of patients' age,routes of administration,drug category,ADR-involved organs or systems and clinical manifestations etc.RESULTS:Of the 1 451 ADR cases,72.16% of the ADR-inducing drugs were administered by intravenous drip,and most were associated with anti-infective drugs,predominantly penicillins,cephalosporins and quinolones.The ADR manifested predominantly as lesions of skin and its appendants.CONCLUSION:Rational drug use and ADR monitoring should be strengthened to reduce or avoid the occurrence of ADR.
Keywords:Adverse drug reaction  Rational drug use  Analysis  Monitoring
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