“化湿通窍液”雾化对慢性鼻-鼻窦炎鼻内镜术后临床疗效及鼻黏膜炎症细胞的影响

目的：探讨“化湿通窍液”雾化吸入对鼻内镜术后患者鼻黏膜转归的影响，并观察术后患者鼻黏膜形态和功能恢复的规律。方法：将经鼻内镜手术治疗的慢性鼻-鼻窦炎（伴有鼻息肉）患者60例随机分为治疗组、对照组各30例，对照组采用生理盐水冲洗鼻腔、术腔；治疗组在对照组治疗的基础上行“化湿通窍液”雾化术腔的方法。观察治疗前后2组患者症状、体征的改变、鼻黏膜纤毛传输速度的变化以及术腔清洁时间、术腔黏膜上皮化时间、炎性细胞数目变化情况。结果：2组在症状、体征、鼻黏膜纤毛传输速度，术腔清洁时间、术腔黏膜上皮化时间、炎性细胞数目等方面相比差异具有统计学意义（P＜0.05）。结论：术后使用中药“化湿通窍液”雾化术腔能更有效地消除鼻黏膜水肿，促进术腔血液循环、分泌物吸收及术腔黏膜再生修复，加快炎症消退，临床疗效明显优于单纯生理盐水冲洗。

Influence of HuaShi TongQiao Liquid Atomization on Clinical Effects of Nasal Endoscope in Treating Chronic Rhinitis-Nasosinusitis and Inflammatory Cells of Nasal Mucosa

Objective：To discuss the effects of HuaShi TongQiao liquid atomization on nasal mucosa recovery of the patients who underwent nasal endoscopic surgery, and observe the laws of functional recovery and the mor-phology of nasal mucosa in postoperative patients. Methods： All 60 patients were randomized into the treatment group and the control group equally, the control group received the rinsing of nasal cavity by physiological saline, and the treatment group HuaShi TongQiao liquid atomization on the foundation of the therapy. The changes of symp-toms and body sign of the patients, the changes of nasal cilia transportation speed, cleaning time of nasal cavity, metaplasia of nasal cavity mucous epithelium and the changes of inflammatory cells number were observed before and after treating. Results：The difference had statistical meaning in the symptom, body signs, nasal cilia transporta-tion speed, cleaning time of nasal cavity, metaplasia of nasal cavity mucous epithelium and inflammatory cells num-ber between both groups （P＆lt;0.05）. Conclusion：Therapeutic effects of HuaShi TongQiao liquid atomization are ob-vious superior to that of washing with physiological saline only after the surgery, which could effectively eliminate the enema of nasal mucosa, promote blood circulation of nasal cavity, the absorption of secreta, regeneration and re-covery of the mucous, and accelerate the rehabilitation of the inflammation.