放射性镍钛合金内支架治疗晚期恶性胆管梗阻

目的 探讨放射性镍钛记忆合金胆道内支撑架对晚期恶性胆管梗阻的治疗效果。方法 通过对比放射性镍钛合金胆道内支架，Wallstent金属内支架，胆肠吻合术在减黄效果，术后并发症，生存时间等方面 疗效，研究放射性镍钛合金胆道内支架在治疗晚期恶性胆管梗阻方面的优越性。结果 三组在减黄效果上无明显差别，但放射性镍钛合金内支架组在无症状生存时间及总的生存时间方向较另两组长，其术后并发症较另两组明显少（P＜0．01），复发率低，而且病人痛苦小，生存质量明显得到提高。结论 放射性镍钛合金胆道支架既能解决晚期恶性胆管梗阻病人因胆道梗阻所致黄疸带来的痛苦，又能有效抑制肿瘤细胞的生长，对于延长病人生存时间，提高生存质量具有切实疗效。

Treatment of advanced malignant biliary obstruction with radioactive nickel-titanium memory alloy stent

Objective To study the therapeutic efficacy of radioactive nickel titanium memory alloy stent in treatment of advanced malignant biliary obstruction. Methods The radioactive nickel titanium memory alloy stent, Wallstent and cholangioenterostomy were compared in patients with advanced malignant biliary obstruction for reducing jaundice, postoperative complications and survival time to determine the superiority of the radioactive nickel titanium memory alloy stent in treatment of the disease. Results The non symptom survival time and total survival time were significantly longer but postoperative complications lower in patients treated with the radioactive nickel titanium memory alloy stent than in those with the other 2 methods (P<0 01). Meanwhile, in patients with the radioactive stent, the recurring rate was low and bitterness little to result in improvement of life quality. Conclusions The radioactive nickel titanium memory alloy stent can not only resolve the bitterness of patients with advanced malignant biliary obstruction but also inhibit the growth of tumor cells. So it can prolong the survival time and improve life quality of the patients.