Waking with the hypothalamus |
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Authors: | Helmut L Haas Jian-Sheng Lin |
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Institution: | (1) Department of Neurophysiology, Heinrich Heine University D?sseldorf, P.O. Box 101007, 40001 D?sseldorf, Germany;(2) Integrative Physiology of Brain Arousal Systems, Lyon Neuroscience Research Center, INSERM U1028-CNRS UMR 5292, Claude Bernard University Lyon 1, 69373 Lyon, France |
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Abstract: | An essential component of the whole-body homoeostasis provided by the hypothalamus is the management of available energy.
This includes the regulation of sleeping and waking, feeding and drinking, body temperature and activity, as well as the endocrinium.
The waking brain, in particular the cerebral cortex, needs to be activated through neuronal pathways ascending from the brainstem
reticular formation (ascending reticular activating system, ARAS) and reaching the cortical structures by a dorsal route through
the thalamus and a ventral route, including the hypothalamus and the basal forebrain. This review concentrates on the more
recently explored ventral route and the hypothalamus with its different regions involved in the control of the waking state. |
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