| 火绒草化学成分的研究 |
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| 引用本文： | 李 礼,张国刚,潘春媛,左甜甜,王胜超. 火绒草化学成分的研究[J]. 中国药物化学杂志, 2009, 19(3): 212-213 |
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| 作者姓名： | 李 礼 张国刚 潘春媛 左甜甜 王胜超 |
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| 作者单位： | 沈阳药科大学 中药学院，辽宁 沈阳 110016 |
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| 摘 要： | 目的 对中药火绒草[Leontopodium leontopodioid (Wild.)Beauv.]进行化学成分研究。方法 应用硅胶柱色谱、薄层制备色谱、葡聚糖凝胶等色谱技术分离纯化，根据理化性质和波谱分析确定化合物的结构。结果 从火绒草中分离得到5个已知化合物，分别为芹菜素-7-O-β-D-葡萄糖苷（1）、木犀草素-7-O-β-D-葡萄糖苷（2）、β-谷甾醇（3）、阿魏酸（4）以及香草酸（5）。结论 化合物1、2为首次从火绒草属植物中分离得到。
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| 关 键 词： | 火绒草；波谱分析；结构鉴定；柱色谱 |
| 收稿时间： | 2008-07-10 |
| 修稿时间： | 2009-02-27 |
Chemical constituents of Leontopodium leontopodioid (Wild.)Beauv. |
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| LI LI,ZHANG Guo-gang,PAN Chun-yuan,ZUO Tian-tian,WANG Sheng-chao. Chemical constituents of Leontopodium leontopodioid (Wild.)Beauv.[J]. Chinese Journal of Medicinal Chemistry, 2009, 19(3): 212-213 |
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| Authors: | LI LI ZHANG Guo-gang PAN Chun-yuan ZUO Tian-tian WANG Sheng-chao |
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| Affiliation: | School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang 110016，China |
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| Abstract: | Aim To investigate the chemical constituents of Leontopodium leontopodioid (Wild.)Beauv. Methods The constituents were isolated on silica gel column chromatography， preparative TLC and Sephadex LH-20 column chromatography，and were identified by physicochemical properties. Their sturctures were elucidated by spectral analysis．Results Five compounds were isolated and identified as apigenin-7-O-β-D-glucoside (1), luteolin-7-O-β-D-glucoside (2),β-sitosterol (3), feruli acid (4) , and vanillic acid (5) . Conclusions Compounds 1,2 were isolated from Leontopodium for the first time. |
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| Keywords: | Leontopodium leontopodioid spectral analysis structural identification column chromatography |
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