伴有抑郁的老年冠心病患者自主神经功能的改变 |
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引用本文: | 杨瑾啸,;孙翠峰,;古丽扎尔·买买提明. 伴有抑郁的老年冠心病患者自主神经功能的改变[J]. 临床精神医学杂志, 2014, 0(4): 255-257 |
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作者姓名: | 杨瑾啸, 孙翠峰, 古丽扎尔·买买提明 |
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作者单位: | [1]湖北医药学院附属太和医院心内科,十堰市442000; [2]新疆医科大学第一附属医院干部病房内二科,十堰市442000; |
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摘 要: | 目的:探讨伴有抑郁老年冠心病患者自主神经功能的改变。方法:根据汉密尔顿抑郁量表(HAMD)、Zung氏抑郁自评量表(SDS)、以及冠状动脉造影结果,将163例住院患者及健康体检者分为冠心病伴抑郁组(48例)、冠心病组(65例)、正常对照组(50例);并行24 h动态心电图检查,分析心率变异各项指标及其与抑郁程度的相关性。结果:与正常对照组相比,冠心病伴抑郁组与单纯冠心病组,时域指标均下降,频域指标中低频功率(LF)、LF/高频功率(HF)值上升。冠心病伴抑郁组的抑郁严重度与24 h正常RR间期标准差(SDNN)呈负相关,与LF/HF之间呈正相关(r=-0.967,r=0.971,P均0.05)。结论:伴有抑郁症状老年冠心病患者自主神经功能改变更明显,并与抑郁程度相关。
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关 键 词: | 老年冠心病 抑郁 自主神经功能 |
Changes of autonomic nervous function in elderly coronary heart disease Patients accomPanied by de-Pression |
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Affiliation: | Yang Jin-xiao, SUN Cui-feng( Gulizhaer Maimaitiming the First Affiliated Hospital of Xinjiang Medical University, Urumuqi 830000, China) |
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Abstract: | To explore the changes of autonomic nervous function in elderly coronary heart disease(CHD)patients accompanied by depression. Method:According to the scores of Hamilton depres-sion rating scale(HAMD),Zung self-rating depression scale(SDS),and the results of coronary angiography, 163 inpatients and health persons were divided into CHD with depression group(48 cases),CHD group(65 ca-ses)and normal control(NC)group(50 cases). They were monitoried by 24 h dynamic electrocardiogram. The index of heart rate variability(HRV)and its correlation with depressive severity were analyzed. Results:Compared to NC group,the time domain index of HRV were significantly lower;the mean value of the low-fre-quency(LF)power in the frequency domain index,and the value of LF/ high-frequency(HF)power were signif-icantly increased in CHD with depression group and CHD group. The depressive severity was negatively correlated with 24 h normal phase standard deviation(SDNN)and positive correlated with LF/ HF in CHD patients accom-panied by depression(r = - 0. 967,r = 0. 971,all P ﹤ 0. 05). Conclusion:The change of autonomic nervous function in CHD patients accompanied by depression is more obvious and correlated with depressive severity. |
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Keywords: | elderly coronary heart disease depression cardiac autonomic nervous function |
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