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降钙素原预测创伤及外科术后院内感染的研究
引用本文:文舜康,陈怀生,温隽珉,张华东,洪澄英. 降钙素原预测创伤及外科术后院内感染的研究[J]. 现代预防医学, 2011, 38(5): 963-964,970
作者姓名:文舜康  陈怀生  温隽珉  张华东  洪澄英
作者单位:暨南大学医学院第二临床学院,深圳市人民医院ICU,深圳,518020
摘    要:[目的]通过监测外科手术、创伤病人入ICU时的降钙素原(PCT)水平,评估PCT对外科手术、创伤病人院内感染的预测作用。[方法]纳入年龄大于18岁、创伤或手术后需要进入ICU监护的病人73例。监测PCT水平及院内感染情况。[结果]PCT≥0.05ng/ml预测外科术后、创伤病人院内感染的敏感度为100%,特异度37.5%,准确度71.2%,阳性预测值32.7%,阴性预测值100%,阳性似然比1.60,阴性似然比为0。PCT≥0.25ng/ml预测外科术后、创伤病人院内感染的敏感度为37.5%,特异度97.0%,准确度64.4%,阳性预测值93.8%,阴性预测值56.1%,阳性似然比12.5,阴性似然比为0.64。入ICU的PCT值预测外科术后、创伤病人院内感染的ROC曲线下面积为0.893。[结论]对创伤及外科手术后病人进行PCT监测,有助于早期发现院内感染高危病人,可指导临床抗生素治疗。

关 键 词:创伤  手术  院内感染  降钙素原  预测

STUDY ON PROCALCITONIN IN PREDICTION FOR NOSOCOMIAL INFECTION AFTER TRAUMA AND SURGERY
WEN Shun-kang,CHEN Huai-sheng,WEN Jun-min,et al.. STUDY ON PROCALCITONIN IN PREDICTION FOR NOSOCOMIAL INFECTION AFTER TRAUMA AND SURGERY[J]. Modern Preventive Medicine, 2011, 38(5): 963-964,970
Authors:WEN Shun-kang  CHEN Huai-sheng  WEN Jun-min  et al.
Affiliation:WEN Shun-kang,CHEN Huai-sheng,WEN Jun-min,et al.(Second Clinical Medicine College,Jinan University,Shenzhen 518020,China)
Abstract:[Objective]To assess the predictive effects of procalcitonin(PCT)on trauma and surgery patients for nosocomial infection by monitoring PCT level.[Methods]Seventy-three patients who were older than 18-year and needed ICU monitoring after surgery or trauma were included and monitored PCT and nosocomial infection.[Results]The sensitivity of nosocomial infection prediction with PCT more than 0.05ng/ml after surgery and trauma was 100%.The specificity was 37.5%.The accuracy was 71.2%.The positive predictive valu...
Keywords:Trauma  Surgery  Nosocomial infection  Procalcitonin  Prediction  
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