| 苯妥英钠和甲状腺素的关系 |
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| 引用本文： | 印美韵 洪震. 苯妥英钠和甲状腺素的关系[J]. 中国临床药学杂志, 1999, 8(1): 30-32 |
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| 作者姓名： | 印美韵 洪震 |
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| 作者单位： | 上海医科大学华山医院种经内科 上海200040 |
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| 摘 要： | 目的；研究苯妥英钠和甲状腺素之间的关系。方法：测定２９例单用苯妥钠病人的血清甲状腺素。结果；其中１例ＦＴ４低于正常值，２例ＴＴ４低于正常值，所有病人没有甲状腺功能低下的临床表现：结论：选用苯妥英钠作为抗癫痫药物时需考虑与内分泌疾病的关系。对甲状腺功能低下的病人尽量不用苯妥英钠。应用苯妥英钠治疗癫痫的病人一般不需加用甲状腺素。
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| 关 键 词： | 苯妥英钠 甲状腺素 癫痫 |
The relationship between phenytoin sodium and thyroid hormone |
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| Yin Meiyun,Hong Zheng,Hao Zhongzhun. The relationship between phenytoin sodium and thyroid hormone[J]. Chinese Journal of Clinical Pharmacy, 1999, 8(1): 30-32 |
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| Authors: | Yin Meiyun Hong Zheng Hao Zhongzhun |
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| Affiliation: | Yin Meiyun,Hong Zheng,Hao Zhongzhun Department of Neurology,Huashan Hospital,Shanghai Medical University,Shanghai 200040 |
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| Abstract: | AIM : To study the relationship between phenytoin sodium and thyroid hor-mone. MRTHODS:In this study,the thyroid hormone level was tested in 29 patients treated with phenytoin sodium only. RESULTS:It was found that 1 FT4 level and 2 TT4 levels were lower than the normal range. None of the 29 patients had clinical picture of hypothyroidism. CONCLUSION :So the relationship between phenytoin sodium and endocrine diseases should be concerned while select the phenytoin sodium as an anti-epileptic drugs. It is recommended not to use this medicine in patients with hypothyroidism. To the patients using phenytoin so-dium,it normally does not need to add thyroxin. |
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| Keywords: | phenytoin sodium thyroid hormone epilepsy |
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