张力平衡针法对脑梗死患者血清IL-1和sICAM-1、sVCAM-1的影响

目的探讨张力平衡针法对脑梗死患者(RCI)血清白细胞介素-1(IL-1)和可溶性细胞间黏附分子-1(sICAM-1)、可溶性血管细胞黏附分子-1(sVCAM-1)含量的影响.方法选择RCI患者82例,采用张力平衡针法与传统针法进行对照,并采用酶联免疫吸附法(ELISA)测定患者血清IL-1和sICAM-1、sVCAM-1含量的变化.结果RCI患者IL-1及sICAM-1、sVCAM-1的水平显著高于健康组(P<0.05),且sICAM-1、sVCAM-1均与IL-1呈正相关(r=0.743,P<0.001;r=0.862,P<0.001).两组对3项指标均有一定的改善作用,张力平衡针法组优于传统针刺组(P<0.01).结论张力平衡针法改善神经功能的作用可能与降低IL-1及sICAM-1、sVCAM-1的水平有关.

Effects of different point association needling methods on IL-1, sICAM-1 and sVCAM-1 in the patient of cerebral infarction

OBJECTIVE: To observe effects of acupuncture on serum interleukin-1 (IL-1) and soluble intercellular adhesion molecule-1 (sICAM-1) and vascular cell adhesion molecule-1 (sVCAM-1) in the patient of cerebral infarction. METHODS: Eighty-two cases of cerebral infarction were randomly divided into a treatment group treated by balanced muscular tension needling method, and a control group by traditional needling method. The levels of serum IL-1, sICAM-1 and sVCAM-1 were determined with enzyme-linked immunosorbent assay (ELISA). RESULTS: The levels of serum IL-1, sICAM-1 and sVCAM-1 in the patient of cerebral infarction were significantly higher than those in the healthy persons (P < 0.01); there were positive correlation between sICAM-1 or sVCAM-1 level and IL-1 level (r = 0.743, P < 0.001; r = 0.862, P < 0.001). The three indexes improved to a certain extent in the two groups, with the treatment group superior to the control group (P < 0.01). CONCLUSION: The improvement of nervous function by the balanced muscular tension needling method in the patient of cerebral infarction is possibly related with decrease of IL-1, sICAM-1 and sVCAM-1 levels.