Abstract: | In principle, the heart tube of a zebrafish embryo is an impedance pump that drives blood flow forward by compressing the tube periodically and asymmetrically.In this article, we proposed a hypothesis that the blood pumping mechanism of the zebrafish embryo heart tube can be applied to the design of pulsatile ventricular assist devices, which may overcome the shortcomings of current ventricular assist devices such as hemolysis caused by the mechanical injure of blood. |