老年阿尔茨海默病患者认知功能与脑电图异常的关系

目的：探讨老年阿尔茨海默病患者认知功能与脑电图异常的关系。方法对41例老年阿尔茨海默病患者进行脑电图检测，并应用简易智力状态检查表、世界卫生组织‐加利福尼亚洛杉矶大学听觉词语学习测验、画钟测验进行测评分析。结果本组患者中重度痴呆12例，中度痴呆15例，轻度痴呆14例；脑电图轻度异常15例，中度异常14例，重度异常12例；不同程度脑电图异常患者简易智力状态检查表、世界卫生组织‐加利福尼亚洛杉矶大学听觉词语学习测验、画钟测验评分比较差异有极显著性（P＜0．01），痴呆程度比较差异有显著性（P＜0．05）。结论脑电图可作为检测老年阿尔茨海默病患者认知功能的一个客观指标，脑电图检测联合神经心理学测验结果可作为阿尔茨海默病诊治的客观依据。

Relationships between cognitive function and EEG abnormality in senile patients with Alzheimer's disease

Objective To investigate the relationship between cognitive function and EEG abnormality in senile patients with Alzheimer's disease (AD) .Methods EEG detections were carried out in 41 senile AD patients and assessments with the Mini‐Mental State Examination (MMSE) ,World Health Organization‐University of California ,Los Angeles Auditory Verbal Learning Test (WHO‐UCLA AVLT) and Clocking Drawing Test (CDT) .Results Of the patients 12 ones were severe dementia ,15 moderate and 14 mild ;EEG abnormality of 15 patients was mild ,14 moderate and 12 severe;there were very significant differ‐ences in the MMSE ,WHO‐UCLA AVLT and CDT scores among patients with different degrees of EEG abnormalities (P<0 .01) ,comparison differences of dementia degrees were significant (P<0 .05) .Conclu‐sion EEG could be used as an objective indicator for the detection of cognitive function of AD patients , EEG detection plus neuropsychological test results could be used as objectives bases of AD diagnosis and treatment .