抑郁情绪对腹泻型肠易激综合征患者临床症状的影响

目的：探讨抑郁情绪对腹泻型肠易激综合征患者临床症状的影响。方法对84例腹泻型肠易激综合征患者进行生活一般状况、症状程度、抑郁状况筛查，依据汉密顿抑郁量表评分结果将其分为抑郁组和非抑郁组，对两组临床典型症状特征及躯体症状发生率进行对比分析。结果抑郁组临床典型症状严重程度显著重于非抑郁组（P＜0．05），两组发作频率及每次持续时间比较差异有显著性（ P＜0．05或0．01）。抑郁组躯体症状发生率为100％，非抑郁组为33．3％，抑郁组显著高于非抑郁组（χ2＝43．45，P＜0．01）。患者典型症状严重程度、发作频率、持续时间与汉密顿抑郁量表评分呈显著正相关（ P＜0．05或0．01）。结论抑郁情绪可加重腹泻型肠易激综合征患者的典型症状，常表现为明显的躯体症状。

Influences of depressive emotions on clinical symptoms of pa-tients with diarrhea-predominant irritable bowel syndrome

Objective To explore the influences of depressive emotions on clinical symptoms of patients with diarrhea‐predominant irritable bowel syndrome (D‐IBS) .Methods General living status ,symptom degrees and depressive status were screened in 84 D‐IBS patients ,they assigned to depression and non‐de‐pression group according to the Hamilton Depression Scale (HAMD) scores ,and contrastive analyses of typical and physical symptoms incidences conducted between 2 groups .Results The severities of typical symptoms were significantly greater (P< 0 .05) and episode frequencies and duration/time longer (P<0 .05 or 0 .01) in depression than in non‐depression group .The incidence of physical symptoms were re‐spectively 100% in depression and 33 .3% in non‐depression group ,the former significantly higher than the latter (χ2 = 43 .45 ,P< 0 .01) .Patients’ severity of typical symptoms ,episode frequencies and duration were positively related to the HAMD score notably (P<0 .05 or 0 .01) .Conclusion Depressive emotions could aggravate the typical symptoms of D‐IBS patients often exhibiting obvious physical symptoms .