卒中后抑郁患者交感神经皮肤反应特点及临床意义

目的探讨卒中后抑郁(PSD)患者交感神经皮肤反应(SSR)的特点及临床意义。方法共采集脑卒中患者88例,根据汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)评分将脑卒中患者分为无抑郁组、轻中度抑郁组、重度抑郁组,选取22名健康人群作为健康对照组。各组患者分别进行SSR测定,记录首次达峰时间及SSR波幅并进行比较分析。结果本组脑卒中患者PSD发生率为67.05%,PSD组与健康对照组相比,SSR首次达峰时间延长;波幅减低(均P0.05)。PSD组与无抑郁组相比,SSR首次达峰时间延长;SSR波幅减低(P0.05)。重度抑郁组与轻中度抑郁组相比,SSR首次达峰时间延长;SSR波幅减低(均P0.05)。结论 PSD患者SSR明显异常,抑郁越重,其异常程度越明显,SSR检测可有助于PSD诊断。

The characteristic of sympathetic skin response in post-stroke depression and the clinical significance

Objective To explore the characteristic of sympathetic skin response ( SSR) in patients with post-stroke depression ( PSD) and the clinical significance .Methods Eighty-eight patients with stroke were evaluated by the Hamilton Depression Scale ( HAMD ) and the Self-Rating Depression Scale ( SDS ) , and divided into no depression group , mild to moderate depression group and severe depression group , 22 healthy people were introduced into control group .Their SSR was determined , and the first peaktime and amplitude of SSR .The results were compared and analyzed.Results The incidence of PSD was 67.05%in 88 stroke patients.The study group revealed prolonged first peak time and lower amplitude of SSR compared to control group and no depression group ( all P<0.05).The severe depression group exhibited a longer first peak time and a lower amplitude of SSR than mild to moderate depression group ( all P<0.05 ) .Conclusions SSR in patients with PSD are abvious abnormality , the more serous the degree of depression in patients with PSD is , the more obvious the degree of abnormal .SSR may be helpful in diagnosis of PSD is .