Effect of sub-lethal doses of thiamethoxam (a neonicotinoid) on hemato-biochemical parameters in broiler chicks

This project was designed to observe the hemato-biochemical effects of sub-lethal doses of thiamethoxam (TMX) in broiler chicks. A-day old chicks (n?=?90) were procured from the local market and maintained under standard housing conditions and divided into five equal groups (18 birds/group). The experimental trial continued for 45?days. Sub-lethal doses of TMX including 50, 100, 200 and 400?mg/kg B.W. to groups A, B, C and D were administered through crop tube, respectively. Group E served as a control. Blood and serum samples were collected from each group on 10th, 17th, 24th, 31st, 38th and 45th day of the experiment. The data were analyzed through ANOVA by MSTAT-C. All hematological parameters were determined. Serum samples were analyzed for ALT, AST, total proteins and urea. It was concluded from this study that even sub-lethal doses of TMX have toxic effects on hematology and biochemical parameters.