宫颈癌子宫动脉血管网模型的构建及其三维可视化研究

目的：探讨研究宫颈癌子宫动脉血管网的方法及其临床意义。方法 ：用15％的过氯乙烯填充剂对一例宫颈癌离体子宫标本行子宫动脉和卵巢动脉分色灌注并铸型。分别于灌注前后行64层螺旋CT薄层扫描，并以最大密度投影法(MIP)和容积再现(VR)行三维重建。结果：(1)铸型和CT三维重建的宫颈癌子宫动脉血管网模型均可清晰的显示病变部位的血管供应及分布情况、子宫动脉及其分支的走行以及与卵巢动脉的关系；(2)利用CT薄层扫描重建的可视化模型可以从多方面清楚的显示病灶的大小及浸润范围。结论：应用血管铸型和CT薄层扫描技术可成功构建宫颈癌子宫动脉血管网模型，并可了解宫颈癌病灶的浸润范围及其血供特点等，对宫颈癌的诊断和治疗有一定的临床价值。

The model of arterial vascular network of uterus with cervical cancer: the construction and its three-dimensional visualization

        Objective: To explore the method for constructing the model of vascular network of uterus with cervical cancer and discuss its clinical significance. Methods: A set of specimens, including uterus, vagina and uterine adnexa from a cervical cancer patient were infused with 15% perchloroethylene through the uterine artery and the ovarian artery, and then casted. The CT data of the specimen obtained before and after infusion were used to reconstruct 3D uterine arterial network, using the maximum intensity projection (MIP) and volume rendering (VR). Results:(1) The cast specimen and 3D model of uterine arterial vascular network can clearly display the major blood supply of diseased region. (2) The imaging features and anatomical structures of the uterine vascular network could be shown through different points of view on the reconstructed model.  Conclusions: It is an effective way to construct vascular network of uterus through vascular cast combined with CT scan. Basing on the uterine arterial vascular network of cervical cancer patient, we can understand the size of the lesion and its blood supply, which is useful for the diagnosis and treatment of cervical cancer.