台盼蓝与吲哚青绿在成熟期和过熟期白内障手术中的应用

目的：：观察台盼蓝与吲哚青绿在成熟期、过熟期白内障超声乳化手术中进行连续环形撕囊( continuous curvilineal capsulorrhexis, CCC)的作用及效果。方法：选取成熟期、过熟期白内障122例122眼,随机分为3组,台盼蓝染色组( A组)46例46眼,吲哚青绿染色组(B组)40例40眼,对照组(C组)36例36眼。染色组在手术中分别使用台盼蓝或吲哚青绿0.2mL注入前房,进行CCC。术中观察及对比连续环形撕囊成功率、晶状体后囊破裂及人工晶状体囊袋内植入情况。观察术后前房炎症反应,并与对照组进行观察分析。结果：台盼蓝染色组(A组)连续环形撕囊成功率、人工晶状体囊袋内植入率与对照组(C组)进行统计学分析有显著性差异(P<0.05)。吲哚青绿染色组(B组)人工晶状体囊袋内植入率与对照组(C组)进行统计学分析有显著性差异(P<0.05)。晶状体后囊破裂率三组间无显著性差异(P>0.05)。术后观察前房炎症反应三组间无明显差异。结论：应用台盼蓝或吲哚青绿对缺乏红色反光的成熟期、过熟期白内障进行晶状体囊膜染色后再行CCC,目前是一种安全可靠的技术,两者效果相当。手术中可以使连续环形撕囊顺利进行,提高了手术成功率。

Application of trypan blue and indocyanine green in mature and hypermature cataracts

AIM: To assess the efficacy and safety of trypan blue and indocyanine green(ICG)for continuous curvilineal capsulorrhexis(CCC)in mature or hypermature phacoemulsification.

METHODS:A total of 122 eyes of 122 cases with cataracts in mature and hypermature were randomly divided into three groups, trypan blue staining group was 46 eyes of 46 cases as group A, ICG staining group was 40 eyes of 40 cases as group B, control group was 36 eyes of 36 cases as group C. Staining groups were used to 0.2mL trypan blue or ICG injected into the anterior chamber during operation, respectively. The success rate of CCC, lens posterior capsule rupture and implanted intraocular lens pouch were observed and compared during operation. Anterior chamber inflammation was observed after operation, and compared with the control group to observe and analysis.

RESULTS:The success rate of CCC, implanted intraocular lens pouch were statistically significant difference in trypan blue staining group(group A)than that in control group(group C)(P<0.05). Implanted intraocular lens pouch was statistically significant difference in ICG group(group B)than that in control group(group C)(P<0.05). The rate of lens posterior capsule rupture was no statistically significant difference in all three groups(P>0.05). Anterior chamber inflammation was no significant difference in the postoperative reaction among the three groups.

CONCLUSION:The application of trypan blue or ICG for lens capsule staining before CCC in lack of red reflective mature and hypermature cataracts is safe and effective, both results are comparable. It guarantees a complete CCC and improves the success rate of phacoemulsification.