本院急性胰腺炎抗菌药物应用回顾性分析

目的：调查本院急性胰腺炎抗菌药物应用现状，探讨总结急性胰腺炎的抗菌药物合理应用原则及方法。方法：对2008年1月至12月消化科93例急性胰腺炎患者的临床资料和抗菌药物使用情况进行回顾分析。结果：93例急性胰腺炎患者中，轻型胰腺炎78例，占83．67％；重症胰腺炎15例，占16．13％。抗菌药物预防性应用存在过度用药现象，抗菌药物联合应用方面大部分未做到按照指南用药，用药疗程合理的仅占30％。感染病例细菌培养送检率低，经验用药现象严重。结论：急性胰腺炎抗菌药物应用存在不合理表现，应根据“个体化治疗结合指南”的原则及时合理选择抗菌药物。

Retrospective analysis of antibacterial agents utilization in acute pancreatitis patients

AIM： To examine the rational use of antibiotics in acute pancreatitis of Xi-Jing hospital. METHODS： Retrospective analysis 93 patients who were provided with antibiotics drugs of acute pancreatitis patients from January to December of 2008. RESULTS ： There are 93 AP eases in the Degestion Medical Department. 78 MAP eases account for 83.67%, 15 SAP eases account for 16.13%. Exeessus-medieation were found in prophylaxis utilization in antibaeterials drug, for the bulk of antibaeterials drug combination was unreasonable, the reasonable course of treatment only account for 30%. The rates of bacterial culture were too low in infection cases, which caused severity experience medication. CONCLUSION： Generally, the choices of antibiotic arc rational, but there are still substandard usage of antibiotics in hospital, and it＇ s necessary to improve the management of rational usage of antibiotics.