236例症状性癫痫病因分析

目的探讨症状性癫痫的病因及不同年龄段病因构成特点。方法对236例症状性癫痫患者的病因特点进行回顾分析。结果 20岁以下及60岁以上症状性癫痫患者起病者各110例。最多见的病因为脑血管病(19.9%),其次为脑外伤(14.4%),药物、毒物及代谢紊乱(12.7%),中枢神经系统感染(12.3%)。20岁以下的患者以颅内感染、皮质发育障碍为多见,2~39岁年龄段则以颅内感染为首位,其次脑血管病(主要为脑缺血和脑血管瘤)、脑肿瘤等;40岁以上的患者以脑血管病为第一位病因,其次是脑外伤、神经系统变性疾病等占多数。结论症状性癫痫常见的病因依次是脑血管病,脑外伤,药物、毒物及代谢紊乱,中枢神经系统感染,且不同年龄段病因的构成明显不同。

Etiology of 236 Symptomatic Epilepsy Patients

Objective To analyse the etiology of symptomatic epilepsy based on a hospital study in China. Methods The etiology of 236 Patients with symptomatic epilepsy was analyzed, Epilepsy was diagnosed according to classification of ILAE, Results The number of initial onset of epilepsy for patients less than 20 and above 60 were 110 and 69 respectively. The analysis of etiologies shows that cerebral vascular disease was in 19.9%, brain trauma in 14.4%, in 12.7% , cerebral infection in 12.3% , Further study shows that cerebral infection, cortical developmental abnormalities, were more common causes in Patients under age of 20 years, cerebral infection, cerebral vascular disease , cerebral tumor were more common for patients at age of 20 ～ 39, cerebral vascular diseases, brain trauma, neurological degenerative diseases were more common for patients above 40 years of age. Conclusion Cerebral vascular disease , brain trauma , drug, toxicity, and metabolic disturbance, cerebral infection are the most common causes of symptomatic epilepsies and the causes for symptomatic epilepsy are significantly different among various ages.