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Acute Tumor Lysis Syndrome Caused by Transcatheter Oily Chemoembolization in a Patient with a Large Hepatocellular Carcinoma
Authors:Noriaki Sakamoto  Shuichi Monzawa  Hidenobu Nagano  Hogara Nishizaki  Yasuaki Arai  Kazuro Sugimura
Affiliation:(1) Department of Radiology, Hyogo Medical Center for Adults, 13-70 Kitaoji, Akashi City Hyogo, 673-8558, Japan;(2) Department of Internal Medicine, Hyogo Medical Center for Adults, 13-70 Kitaoji, Akashi City Hyogo, 673-8558, Japan;(3) Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuou-ku, Tokyo 104-0045, Japan;(4) Department of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunokicho, Kobe City Chuou-ku, Hyogo, 650-0017, Japan;(5) Present address: Division of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuou-ku, Tokyo 104-0045, Japan
Abstract:Acute tumor lysis syndrome results from a sudden and rapid release of products of cellular breakdown after anticancer therapy. Severe alterations of metabolic profile might occur and result in acute renal failure. We present a patient with a large hepatocellular carcinoma who received transcatheter oily chemoembolization and died subsequently of this syndrome. To our knowledge, there has been only one report of this syndrome induced by chemoembolization for hepatocellular carcinoma. This case illustrates the need to anticipate the development of acute tumor lysis syndrome when chemoembolization is planned for a large hepatocellular carcinoma.
Keywords:Neoplasm  Complication, hepatocellular carcinoma   Acute tumor lysis syndrome  Transcatheter oily chemoembolization
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