缺血性脑血管病患者血清一氧化氮水平观察

目的：观察缺血性脑血管病患者急性期和恢复期血清一氧化氮（NO）和一氧化氮合酶（NOS）水平的变化。方法：采用硝酸还原酶法分别检测30例健康人和70例缺血性脑血管病患者急性期和恢复血清NO含量和NOS水平，将其结果进行对照分析。结果：脑血管病患者急性期血清NO明显高于健康人群（P＜0．01），恢复期明显低于急性期略高于健康对照组，但无显著性。结论：脑血管病患者在病程发展过程中NO水平有明显的变化，提示NO对神经细胞有损害和保护的双重作用。

Observation on the level of nitric oxide in the plasma of ischemic cerebrovascular stroke patients

[Objective] To observe the change of the level of nitric oxide (NO) and the enzyme NO synthase (NOS) in the acute and rehabilitate ischemic cerebrovascular stroke patients. [Methods] The level of nitric oxide (NO) and the enzyme NO synthase (NOS) in 30 cases of healthy people and 70 cases of the acute and rehabilitate ischemic cerebrovascular stroke patients were measured and analyzed. [Results] The level of the nitric oxide (NO) in the plasma of the acute ischemic cerebrovascular stroke patients is significantly higher than healthy people ( P < 0.01), while significantly lower in rehabilitative period and slightly higher than that of healthy people. [Conclusion] The change of nitric oxide (NO) in the development of ischemic cerebrovascular stroke patients is significance. It indicates that nitric oxide (NO) has both harming and protecting effects.