Slitrk gene duplication and expression in the developing zebrafish nervous system |
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Authors: | Jennifer Round Brittany Ross Mark Angel Kayla Shields Barbara Lom |
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Affiliation: | Department of Biology and Program in Neuroscience, Davidson College, Davidson, North Carolina |
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Abstract: | Results : As a prelude to examining the functional roles of Slitrks, we identified eight slitrk orthologs in zebrafish and observed that seven of the eight orthologs were actively transcribed in the nervous system at embryonic, larval, and adult stages. Similar to previous findings in mice and humans, zebrafish slitrks exhibited unique but overlapping spatial and temporal expression patterns in the developing brain, retina, and spinal cord. | |
Keywords: | in situ hybridization neuronal development retina spinal cord Danio rerio leucine‐rich repeat (LRR) |
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